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Ferulic Acid (Topical)

4-hydroxy-3-methoxycinnamic acid

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Meta Information

ID:ferulic-acid
Name:Ferulic Acid
Schema Version:2.4_uniform_evidence_2026_06_18

Created

2026-07-02T07:35:59Z

Model

phase-b-topical-claude-opus-4.8

Interactions

Target id:
/intervention/vitamin-c-topical
Target name:
Topical vitamin C
Severity:
moderate
Interaction type:
synergistic
Nature:
relative
Temporal spacing:
Hours before target:
0
Hours after target:
0
Description:
Ferulic acid stabilizes vitamin C and boosts its antioxidant/photoprotective performance (the basis of CE-Ferulic-type serums).
Actionable advice:
Layer or use a combined C+E+ferulic serum in the morning for best photoprotection.
Validation status:
validated_via_class_inference
Evidence tier:
tier_c
Evidence basis:
class_inference_summary
Evidence anchors:
Source url:
Established mechanism / dermatologic practice (no single primary source quoted)
Exact phrase from label:
Ferulic acid stabilizes L-ascorbic acid and augments C+E photoprotection. Well-documented cosmetic formulation science.
Label source:
Class inference
Action type:
informational_none
Target id:
/intervention/vitamin-e-topical
Target name:
Topical vitamin E
Severity:
minor
Interaction type:
synergistic
Nature:
relative
Temporal spacing:
Hours before target:
0
Hours after target:
0
Description:
Ferulic acid stabilizes vitamin E and the C+E combination, enhancing antioxidant capacity.
Actionable advice:
Compatible; part of the classic C+E+ferulic antioxidant trio.
Validation status:
validated_via_class_inference
Evidence tier:
tier_c
Evidence basis:
class_inference_summary
Evidence anchors:
Source url:
Established mechanism / dermatologic practice (no single primary source quoted)
Exact phrase from label:
Ferulic acid stabilizes the tocopherol/ascorbate system. Established.
Label source:
Class inference
Action type:
informational_none