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Gymnema Sylvestre

Gurmar, Meshashringi, Australian Cowplant, Periploca of the woods

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Meta Information

ID:gymnema-sylvestre
Name:Gymnema Sylvestre
Schema Version:2.4_uniform_evidence_2026_06_18

Created

2026-07-02T07:03:07Z

Model

phase-b-newfiles-claude-opus-4.8

Interactions

Target id:
/class/antidiabetic-medications
Target name:
Insulin / sulfonylureas / antidiabetic medications
Severity:
moderate
Interaction type:
adverse
Nature:
relative
Temporal spacing:
Hours before target:
0
Hours after target:
0
Description:
Gymnema stimulates insulin release and lowers blood glucose, adding to diabetes medications and risking hypoglycemia.
Actionable advice:
Blood glucose is best monitored closely, and a prescriber may reduce insulin or sulfonylurea doses.
Validation status:
validated_via_primary_literature
Evidence tier:
tier_b
Evidence basis:
primary_literature_verbatim
Evidence anchors:
Exact phrase from label:
being an effective insulin-releasing agent at nontoxic concentrations;... and being effective at maintaining normoglycemia in vivo in a mouse model and a human cohort with T2DM.
Label source:
Al-Romaiyan et al., Molecules (2024), PMID 38202777.
Action type:
monitor