Meta Information
ID:plant-sterols-stanols
Name:Plant Sterols / Stanols
Schema Version:2.4_uniform_evidence_2026_06_18
Created
2026-07-02T07:04:56Z
Model
phase-b-newfiles-claude-opus-4.8
Interactions
Target id:
/class/fat-soluble-vitamins
Target name:
Fat-soluble vitamins & carotenoids (A, D, E, K, beta-carotene)
Severity:
moderate
Interaction type:
diminishing
Nature:
relative
Temporal spacing:
Hours before target:
0
Hours after target:
0
Description:
Plant sterols/stanols block absorption of cholesterol and can also modestly reduce absorption of fat-soluble vitamins and carotenoids.
Actionable advice:
Eat plenty of carotenoid-rich foods, or take fat-soluble vitamins separately, to offset the small reduction.
Validation status:
validated_via_class_inference
Evidence tier:
tier_c
Evidence basis:
class_inference_summary
Evidence anchors:
Source url:
Established mechanism / class pharmacology (no single primary source quoted)
Exact phrase from label:
Plant sterols competitively reduce intestinal absorption of fat-soluble micronutrients along with cholesterol. Established mechanism.
Label source:
Class inference
Action type:
monitor
Target id:
/intervention/ezetimibe
Target name:
Ezetimibe
Severity:
minor
Interaction type:
synergistic
Nature:
relative
Temporal spacing:
Hours before target:
0
Hours after target:
0
Description:
Both plant sterols and ezetimibe block intestinal cholesterol absorption; effects overlap.
Actionable advice:
Complementary cholesterol-lowering; no specific harm.
Validation status:
validated_via_class_inference
Evidence tier:
tier_c
Evidence basis:
class_inference_summary
Evidence anchors:
Source url:
Established mechanism / class pharmacology (no single primary source quoted)
Exact phrase from label:
Overlapping cholesterol-absorption inhibition; additive/redundant. Mechanistic.
Label source:
Class inference
Action type:
informational_none