Meta Information
ID:procyanidin-c1
Name:Procyanidin C1
Schema Version:2.4_uniform_evidence_2026_06_18
Created
2026-07-02T07:04:56Z
Model
phase-b-newfiles-claude-opus-4.8
Interactions
Target id:
/class/cyp3a4-substrates
Target name:
CYP3A4 substrates
Severity:
minor
Interaction type:
pharmacokinetic
Nature:
relative
Temporal spacing:
Hours before target:
0
Hours after target:
0
Description:
As a flavonoid, procyanidin C1 could modestly inhibit CYP3A4 in the gut, theoretically raising some drug levels.
Actionable advice:
Low clinical significance; monitor narrow-therapeutic-index CYP3A4 drugs.
Validation status:
validated_via_class_inference
Evidence tier:
tier_c
Evidence basis:
class_inference_summary
Evidence anchors:
Source url:
Established mechanism / class pharmacology (no single primary source quoted)
Exact phrase from label:
Flavonoids can inhibit intestinal CYP3A4; theoretical, low-magnitude. Uncertain for procyanidin C1.
Label source:
Class inference
Action type:
informational_none
Target id:
/class/anticoagulants-antiplatelets
Target name:
Anticoagulants / antiplatelets
Severity:
minor
Interaction type:
adverse
Nature:
relative
Temporal spacing:
Hours before target:
0
Hours after target:
0
Description:
Polyphenols may have mild antiplatelet activity.
Actionable advice:
Minor; watch for bruising with blood thinners.
Validation status:
validated_via_class_inference
Evidence tier:
tier_c
Evidence basis:
class_inference_summary
Evidence anchors:
Source url:
Established mechanism / class pharmacology (no single primary source quoted)
Exact phrase from label:
Polyphenol antiplatelet activity; low-magnitude additive effect.
Label source:
Class inference
Action type:
monitor