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Zinc (Topical)

Zinc Oxide, Zinc Pyrithione, Zinc Sulfate

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Meta Information

ID:topical-zinc
Name:Topical Zinc
Schema Version:2.4_uniform_evidence_2026_06_18

Created

2026-07-02T07:35:59Z

Model

phase-b-topical-claude-opus-4.8

Interactions

Target id:
/intervention/sunscreen
Target name:
Sun protection
Severity:
minor
Interaction type:
synergistic
Nature:
relative
Temporal spacing:
Hours before target:
0
Hours after target:
0
Description:
Zinc (as zinc oxide) is itself a physical sunscreen and is soothing; it complements sun protection.
Actionable advice:
Zinc oxide provides broad-spectrum physical UV protection; compatible with other actives.
Validation status:
validated_via_class_inference
Evidence tier:
tier_c
Evidence basis:
class_inference_summary
Evidence anchors:
Source url:
Established mechanism / dermatologic practice (no single primary source quoted)
Exact phrase from label:
Zinc oxide is a physical sunscreen and anti-inflammatory. Dermatologic practice.
Label source:
Class inference
Action type:
informational_none
Target id:
/class/exfoliating-acids
Target name:
Exfoliating acids / retinoids
Severity:
minor
Interaction type:
synergistic
Nature:
relative
Temporal spacing:
Hours before target:
0
Hours after target:
0
Description:
Topical zinc is soothing and can help calm irritation from stronger actives.
Actionable advice:
Compatible; can help buffer irritation.
Validation status:
validated_via_class_inference
Evidence tier:
tier_c
Evidence basis:
class_inference_summary
Evidence anchors:
Source url:
Established mechanism / dermatologic practice (no single primary source quoted)
Exact phrase from label:
Zinc is anti-inflammatory and broadly compatible. Dermatologic practice.
Label source:
Class inference
Action type:
informational_none